MEET YOUR MENTOR!

His clinical area of interest is the (endovascular) treatment of (complex) aortic pathology and peripheral vascular disease, including diabetic foot. His main research focus areas are vascular biology (aneurysm and atherosclerosis), vascular tissue engineering, and innovative endovascular techniques. He is the inventor of the MAZE Box, a new hands-on simulator for endovascular surgery, and co-director of the European Vascular Course.

At the Erasmus MC, her current research focuses on prognosis and clinical and shared decision making in cardiovascular interventions, with special attention to male-female differences. Her research at RSM broadly focuses on network analysis, with a particular focus on women’s organisations as  well as personal networks. 

His research focuses on risk prediction and preventive treatment of unruptured intracranial aneurysms, the diagnosis of (aneurysmal) subarachnoid hemorrhage, and the prevention and treatment of in-hospital complications following subarachnoid hemorrhage, including rebleeding, delayed cerebral ischemia, hydrocephalus, and infections, as well as their impact on patient outcomes. 

As a clinical researcher, she works on image-guided endovascular treatments for vascular diseases in the brain, such as aneurysms and arteriovenous malformations. Irene studies and implements improvements in these treatments, using new imaging techniques and artificial intelligence. 

He investigates various treatments for neurovascular disorders such as aneurysms, focusing primarily on open surgery and endovascular procedures. He also investigates treatments that can counteract the delayed damage that occurs in a subset of patients approximately one week after endovascular procedures. 

He leads translational cardiovascular projects, focusing on engineering myocardial tissue akin to the human heart. In addition, he works on clinical research regarding aortic root surgery, aortic surgery, dissections, endocarditis and mechanical circulatory support (MCS) for heart failure. By building on an extensive disease modelling toolbox, ranging from the lab, to animals to tissue models, he aims to improve health for all patients with cardiovascular disease.   

Her research focuses on the etiology, new imaging techniques, and treatment of aortic aneurysms and dissections by using biobanking, patient's specific cells, data platforms, advanced imaging and artificial intelligence. She also studies treatment of aortic occlusive diseases with microbubbles and nanomedicine techniques. Alongside her research activities, she has extensive clinical expertise in complex endovascular aortic repair.

He studied patient outcomes after tricuspid valve interventions. His current research focuses on big data in cardiothoracic surgery, epidemiology and advanced statistical analyses of observational data. Furthermore, he is a consultant at the EUROMACS registry, the database coordinator of the HVS aortic valve database and the research fellow of the heart valve disease standard dataset at the international consortium of health outcome measurement. 

The focus of his current work is elucidating the molecular mechanisms by which vascular remodeling is initiated and propagated. Key cellular events include phenotypic switching of vascular smooth muscle cells (SMCs) and the role of oxidative stress, extracellular vesicles, and calcification. He aims to elucidate the molecular mechanisms of vascular remodeling in health and vascular disease using primary and iPSC patient derived SMCs. 

Her research focuses on modeling the mechanobiology of native and engineered cardiovascular tissues using integrated computational and experimental methods, in order to obtain an improved understanding of the biological mechanisms responsible for soft tissue development, homeostasis, and disease, and to translate those findings into novel therapies in the field of regenerative medicine.  

His research focuses on the methodology behind current research into the treatment of intracranial aneurysms. His clinical research encompasses cerebrovascular pathology, aneurysms, AVMs and pediatric cerebrovascular disease in the broadest sense. Another area of research encompasses most effective training modalities and programmes for microsurgery. 

The overall aim of her research is to identify patients who are at high risk of developing intracranial aneurysms and subsequent aneurysmal subarachnoid hemorrhages. It is her ambition to increase insight in underlying disease processes, improve detection of aneurysms in high risk patients and optimize treatment. Her research has a strong translational view in which she combines genetics, epidemiology and imaging of intracranial aneurysms. 

Her research focuses on unraveling the molecular mechanisms that drive vascular aging and aneurysm development. She investigates how therapeutic and dietary interventions influence these processes, with the ultimate goal of identifying compounds that slow vascular aging, improve vascular health, and extend healthspan. Ingrid is a board member of the Erasmus MC Cardiovascular Institute and leading research coordinator.